Category Archives: Calorie restriction

Resveratrol Controversy Clarified

Longstanding questions about how the red-wine ingredient resveratrol works at the molecular level have been answered by Harvard’s David Sinclair and colleagues in a paper that just appeared in Science. The new research supports the idea that the compound directly activates an enzyme called SIRT1 to induce effects in cells that are similar to those [...]
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On Calorie Restriction, Monkeys, Magic and Medicine

Since 1935, scientists have known that putting rodents on very low calorie diets extends their lifespans. Scores of studies since then have shown that such calorie restriction (CR) can extend lifespan across species in a way suggesting it delays the onset of diseases of aging, extending healthspans (the proportion of life spent in good health) [...]
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