Category Archives: Obesity and aging

Rapamycin’s Anti-Aging Promise: Mirage or Not?

The first strong evidence that a drug could slow aging in mammals came out in 2009 when scientists reported that chronically feeding doses of rapamycin to mice significantly extended their average and maximum lifespans. Yet rapamycin, a drug used to help prevent rejection of transplanted organs, causes multiple side effects in people, including elevated triglycerides [...]
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Did a Gerontogene Halt Peter Pan’s Sexual Development?

It’s not every day that scientists base a study on an idea behind the story of Peter Pan. But as the research showed, the notion that slow development goes with longer life—which in the immortal Peter’s case meant completely arrested development along with no aging—has implications that reach far beyond Neverland: Led by Rong Yuan [...]
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Yes, Red Wine May Hold Some Answers. Recheck Dosage.

If you’ve tuned into the resveratrol story over the past five years, you’ve probably heard that you’d need to take giant doses of the red-wine ingredient to do any good. That idea was based on mouse studies in 2006 that showed massive doses of the compound blocked bad effects of eating too much fat. A [...]
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Sirtuin News For Mammals

The negative buzz about sirtuins recently grew louder when Science ran a lengthy news piece on Dec. 2 titled, “Aging Genes: The Sirtuin Story Unravels.” The article played up studies in lower organisms casting doubt on earlier high-profile reports that sirtuin enzmes play major roles in aging, which in turn challenged the idea that they [...]
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Vitamin pills and healthy aging

The idea that taking vitamin pills can’t hurt and might do some good recently became a harder sell after two studies suggested that the pills may actually increase the risk of death. In one study, involving more than 38,000 older women, taking a daily multivitamin was found to be associated with a 2.4% higher risk [...]
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Does obesity speed up aging?

Obesity is a major risk factor for a list of diseases that seems to be getting longer every week. Recent additions include metastasizing prostate cancer and cirrhosis of the liver. Over the past few years, brain shrinkage and Alzheimer’s disease have been added, as have arthritis, various cancers, and even incontinence. Scanning the multitude of [...]
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