Category Archives: Resveratrol
Did a Gerontogene Halt Peter Pan’s Sexual Development?
It’s not every day that scientists base a study on an idea behind the story of Peter Pan. But as the research showed, the notion that slow development goes with longer life—which in the immortal Peter’s case meant completely arrested development along with no aging—has implications that reach far beyond Neverland: Led by Rong Yuan [...]
Also posted in aging, David Sinclair, Genetics of aging, Life Span, Obesity and aging Tagged aging, gerontogenes, longevity Comments closed
Yes, Red Wine May Hold Some Answers. Recheck Dosage.
If you’ve tuned into the resveratrol story over the past five years, you’ve probably heard that you’d need to take giant doses of the red-wine ingredient to do any good. That idea was based on mouse studies in 2006 that showed massive doses of the compound blocked bad effects of eating too much fat. A [...]
Also posted in aging, Diet and aging, Drugs and aging, Genetics of aging, Life Span, Obesity and aging, Sirtuins Tagged aging, Hypertension, lifespan, longevity, red wine, SIRT1, Sirtuins Comments closed
Sirtuin News For Mammals
The negative buzz about sirtuins recently grew louder when Science ran a lengthy news piece on Dec. 2 titled, “Aging Genes: The Sirtuin Story Unravels.” The article played up studies in lower organisms casting doubt on earlier high-profile reports that sirtuin enzmes play major roles in aging, which in turn challenged the idea that they [...]
Also posted in aging, David Sinclair, Drugs and aging, Genetics of aging, Life Span, Obesity and aging, Sirtuins Tagged aging, anti-aging, GlaxoSmithKline, lifespan, longevity, Pfizer, Resveratrol, Sinclair, SIRT1, Sirtuins Comments closed
More on Demi, Ashton and Aging
If you’re tracking developments in aging research, don’t miss the issue of National Enquirer that hit newsstands today (dated Feb. 28)—it contains a full-page spread based on the Ashton-Demi Gerontology Seminar on the Beach that graced celebrity news outlets last week. You might also want to take a look at the related piece I did [...]
Also posted in aging, Diet and aging, Drugs and aging, Happiness and Aging, Life Span Tagged aging, Ashton Kutcher, celebrities, Demi Moore, depression, Hollywood, inflammation, omega-3, stress, telomeres, Youth Pill Comments closed
Yet another twist on sirtuins—with leaping ant queens
It’s not often that 33 scientists jointly pen a public complaint that an article in Science got things wrong. But in this week’s issue of Science nearly three dozen researchers working on sirtuins, the enzymes thought by many scientists to help induce the health- and longevity-promoting effects of calorie restriction (CR), complain in a letter [...]
Also posted in David Sinclair, Sirtuins Tagged aging, Resveratrol, Sinclair, SIRT1, Sirtris, Sirtuins Comments closed
Two new twists on resveratrol
A couple of significant developments in the resveratrol story occurred this week, but so far the media has focused only on the less important one of the two. I’ll get to the truly important news in a moment. First, here’s the story that hit the wires yesterday: The Healthy Lifespan Institute, a nonprofit cofounded by [...]
Also posted in David Sinclair, Sirtuins Tagged aging, GlaxoSmithKline, lifespan, Pfizer, Resveratrol, Sinclair, SIRT1, Sirtris, Sirtuins, Westphal Comments closed
On resveratrol and the beautiful mindset of Michael Faraday — Part 2
If I’m conversant with apparently sound research that conflicts with the Sinclair/Sirtris take on resveratrol and sirtuins, you might ask, why haven’t I joined the skeptics who dismiss that take as a house of cards? It’s simple: There are a lot more studies—including a number of compelling in vivo experiments by researchers with no ties [...]
Also posted in David Sinclair, Sirtuins Tagged aging, Pfizer, Resveratrol, Sinclair, SIRT1, Sirtris, Sirtuins Comments closed
On resveratrol and the beautiful mindset of Michael Faraday — Part 1
In recent months, life-science blogs and journals have pulsated with negative vibes about resveratrol, the red-wine ingredient reported to show anti-aging effects in various animal species. The bad vibes have also been directed at sirtuins, the enzymes thought to mediate resveratrol’s benefits and at David Sinclair, the Harvard scientist who first reported that resveratrol can [...]
Also posted in David Sinclair, Sirtuins Tagged aging, Pfizer, Resveratrol, Sinclair, SIRT1, Sirtris, Sirtuins Comments closed
Resveratrol Controversy Clarified