Tag Archives: lifespan

On Calorie Restriction, Monkeys, Magic and Medicine

By admin | Published: August 30, 2012
Since 1935, scientists have known that putting rodents on very low calorie diets extends their lifespans. Scores of studies since then have shown that such calorie restriction (CR) can extend lifespan across species in a way suggesting it delays the onset of diseases of aging, extending healthspans (the proportion of life spent in good health) [...]
Posted in aging, Calorie restriction, Diet and aging, Genetics of aging, Life Span, Monkeys and aging | Also tagged , , , , | Comments closed

Rapamycin’s Anti-Aging Promise: Mirage or Not?

By admin | Published: July 11, 2012
The first strong evidence that a drug could slow aging in mammals came out in 2009 when scientists reported that chronically feeding doses of rapamycin to mice significantly extended their average and maximum lifespans. Yet rapamycin, a drug used to help prevent rejection of transplanted organs, causes multiple side effects in people, including elevated triglycerides [...]
Posted in aging, Diet and aging, Life Span, Obesity and aging, Rapamycin, TOR and aging | Also tagged , , , , , | Comments closed

A New Study On High-Speed Aging

By admin | Published: January 6, 2012
Several people emailed me recently for my reaction to media stories on a University of Pittsburgh study in which the short lifespans of mice with a severe form of progeria (accelerated aging) were extended by injections of stem-cell-like muscle cells from young mice. So I took a look at the study and some related research, [...]
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Yes, Red Wine May Hold Some Answers. Recheck Dosage.

By admin | Published: December 16, 2011
If you’ve tuned into the resveratrol story over the past five years, you’ve probably heard that you’d need to take giant doses of the red-wine ingredient to do any good. That idea was based on mouse studies in 2006 that showed massive doses of the compound blocked bad effects of eating too much fat. A [...]
Posted in aging, Diet and aging, Drugs and aging, Genetics of aging, Life Span, Obesity and aging, Resveratrol, Sirtuins | Also tagged , , , , , | Comments closed

Sirtuin News For Mammals

By admin | Published: December 12, 2011
The negative buzz about sirtuins recently grew louder when Science ran a lengthy news piece on Dec. 2 titled, “Aging Genes: The Sirtuin Story Unravels.” The article played up studies in lower organisms casting doubt on earlier high-profile reports that sirtuin enzmes play major roles in aging, which in turn challenged the idea that they [...]
Posted in aging, David Sinclair, Drugs and aging, Genetics of aging, Life Span, Obesity and aging, Resveratrol, Sirtuins | Also tagged , , , , , , , , | Comments closed

Two new twists on resveratrol

By admin | Published: August 13, 2010
A couple of significant developments in the resveratrol story occurred this week, but so far the media has focused only on the less important one of the two. I’ll get to the truly important news in a moment. First, here’s the story that hit the wires yesterday: The Healthy Lifespan Institute, a nonprofit cofounded by [...]
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