Tag Archives: mTOR

Rapamycin’s Anti-Aging Promise: Mirage or Not?

The first strong evidence that a drug could slow aging in mammals came out in 2009 when scientists reported that chronically feeding doses of rapamycin to mice significantly extended their average and maximum lifespans. Yet rapamycin, a drug used to help prevent rejection of transplanted organs, causes multiple side effects in people, including elevated triglycerides [...]
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Scientific American on TOR and Aging

If you follow aging science—and my guess is that you’re one of those mortal, aging types who do—you might want to take a look at the latest issue of Scientific American (the January 2012 issue), which has a cover story I wrote for the magazine about research on target of rapamycin (TOR) and its implications [...]
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Does obesity speed up aging?

Obesity is a major risk factor for a list of diseases that seems to be getting longer every week. Recent additions include metastasizing prostate cancer and cirrhosis of the liver. Over the past few years, brain shrinkage and Alzheimer’s disease have been added, as have arthritis, various cancers, and even incontinence. Scanning the multitude of [...]
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